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and irreversible inhibitor of CYP17A1 with antiandrogen activity
white blood count
PubMed PMID: 19405107
5-7H2/t10-
in a first-in-human study
L-Epinephrine (Bitartrate) 60200 and irreversible inhibitor of CYP17A1DA 7867 is a novel oxazolidinone. In vitro activities of DA 7867 were compared to those of linezolid and commonly used antimicrobials. DA 7867 had the lowest MIC for 90% of the aerobic gram positive bacterial strains tested, < =0. 25 micro g ml, and it was more potent than linezolid. The in vitro activities of DA 7867, were compared to those of linezolid in 67 susceptible and drug resistant clinical isolates of Mycobacterium tuberculosis. DA 7867 was
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